A cost-minimization analysis of combination therapy in hypertension: fixed-dose vs extemporary combinations
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چکیده
منابع مشابه
Fixed-dose combination Therapy in Hypertension: Focus on Fixed-dose combination of Amlodipine and Valsartan (exforge®)
Hypertension is the leading cause of disability and cardiovascular mortality world-wide. Approximately one-third of the US adult population and over a billion people world-wide have hypertension. Despite increased awareness of hypertension and availability of many effective antihypertensive agents, only one third of patients achieve their target blood pressure (BP). All expert panels now recomm...
متن کاملRational approaches to the treatment of hypertension: drug therapy—monotherapy, combination, or fixed-dose combination?
Blood pressure (BP) control is inadequate worldwide. Many clinical trials suggest that BP is not satisfactorily controlled using monotherapy in most patients. Free drug or fixed-dose combinations are other therapeutic options. The advantages and disadvantages for different treatment approaches are discussed in this review.
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Medicines are weapons used to fight ailments and diseases. More than one medicine is often used for treatment of either single ailment or multiple co-morbid conditions. Most of the modern medicines are potent chemicals having specific and characteristic physical, chemical, pharmacological and therapeutic properties. These properties vary from drug to drug. The dose, route and the regimen of a d...
متن کاملFixed-dose triple-combination treatments in the management of hypertension.
Hypertension remains uncontrolled in approximately 50% of patients with hypertension, which increases the risk of cardiovascular morbidity and mortality in these individuals. A key factor contributing to poor blood pressure (BP) control is nonadherence to prescribed antihypertensive medications. Improving patient adherence to antihypertensive therapy is the key to improving BP goal attainment. ...
متن کاملFixed-dose combinations improve medication compliance: a meta-analysis.
BACKGROUND Compliance with treatment is a sine qua non for successful treatment of chronic conditions like hypertension. Fixed-dose combinations are designed to simplify the medication regimen and potentially improve compliance. However the data on comparison of fixed-dose combination with free-drug regimen to improve patient's medication compliance is limited. METHODS We conducted a MEDLINE ...
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ژورنال
عنوان ژورنال: Farmeconomia. Health economics and therapeutic pathways
سال: 2013
ISSN: 2240-256X
DOI: 10.7175/fe.v14i4.886